Evaluation of an Immunochromatographic Assay Kit for Rapid detection of Mycobacterium tuberculosis in Clinical Isolates

Abstract

Abstract: Objective To evaluate a new immunochromatographic assay (ICA) for rapid discrimination betweenMycobacterium tuberculosisand non-tuberculosis mycobacteria (NTM) in clinical isolates. Method 290 clinical isolates including 175Mycobacterium tuberculosis , 65 NTM, 38 bacteria, 12 fungal isolates were detected using an ICA kit. Results The sensitivity and specificity of the kit were 98.9% (173/175) and 100% (115/115). Conclusions The ICA can detect rapidly and effectivelyMycobacterium tuberculosisin clinical isolates.

Key words: Mycobacterium tuberculosis, Mycobacterium, Antigens, bacterial, Bacterial Proteins, reagent kits, diagnostic

CLC Number:

R446.6

Han Min,Yue Jun. Evaluation of an Immunochromatographic Assay Kit for Rapid detection of Mycobacterium tuberculosis in Clinical Isolates[J]. Chinese Journal of Antituberculosis, 2010, 32(5): 57-59.

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Evaluation of an Immunochromatographic Assay Kit for Rapid detection of Mycobacterium tuberculosis in Clinical Isolates

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