Abstract: ObjectiveTo compare the Results of drug susceptibility tests (DST) of Mycobacterum tuberculosis (MTB) using the proportion method and the absolute concentration method. MethodsWe adopted the absolute concentration method and the proportion method to detect the susceptibility to four anti-tuberculosis drugs (RFP, EMB, SM, INH) of 2946 MTB strains in the same time. ResultsThe accordance of the Results of four drug susceptibility tests between the proportion method and the absolute concentration method was 97.8%, 96.7%, 94.3%, 92.3%, respectively, and there were significant difference between the Results of two methods（P<0.05）. ConclusionsThere was a high general accordance between the proportion method and the absolute concentration method for the DST of MTB. But the statistic difference should be paid attention.

Key words: Mycobacterum tuberculosis, microbial susceptibility tests