Abstract: Objective To discuss the operation indication for pulmonary tuberculosis with drug resistance.Methods Reviewing 7 000 cases of pulmonary tuberculosis in which 36 cases with drug resistance that have been operated in our hospital from 1990～1997.Results The cure rate of 36 cases of pulmonary tuberculosis with drug resistance is 94%,sputum negative conversion rate is 84%,and the incidence rate of complication is 13%.Conclusion It is feasible for some patients who have 2～3 kinds of drug resistance to receive surgical treatment.It can improve the cure rate of drug resistance pulmonary tuberculosis but the complication rate of patients who have at lease 4 kinds of drug resistance is high,so that more prudent indication criteria should be considered.

Key words: Tuberculosis,pulmonary/Surgery operation, Drug resistance