Advances in detection of drug resistance of Mycobacterium tuberculosis

doi:10.3969/j.issn.1000-6621.2019.02.019

Abstract

Abstract:

Detection of drug-resistant genes of Mycobacterium tuberculosis is one of the difficult problems in diagnosis and treatment of tuberculosis. In recent years, many methods have been used to detect drug-resistant genes. The author summarized the research progress of drug-resistant detection methods of Mycobacterium tuberculosis in three respects as follows: the detection kits with registration certificates in China,the detection kits with registration certificates in the world that have not yet entered into China and new methods of preclinical research.

Key words: Mycobacterium tuberculosis, Drug resistance,bacterial, Diagnostic techniques and procedures, Review literature as topic

Jun-xian ZHANG,Xue-qiong WU. Advances in detection of drug resistance of Mycobacterium tuberculosis[J]. Chinese Journal of Antituberculosis, 2019, 41(2): 227-232. doi: 10.3969/j.issn.1000-6621.2019.02.019

References 41

[1]	陈小蓉, 张侠, 茅惠娟 . BACTEC MGIT 960系统与改良罗氏培养基抗酸分枝杆菌药敏结果的评估. 第一军医大学学报, 2005,25(9):1195-1196.
[2]	杨顺利, 布红丽, 范梦柏 . BACTEC MGIT 960快速药敏与罗氏比例法药敏检测方法对比. 临床医药实践, 2015,24(12):919-921.
[3]	Zhao P, Fang F, Yu Q , et al. Evaluation of BACTEC MGIT 960 system for testing susceptibility of Mycobacterium tuberculosis to first-line drugs in China. PLoS One, 2014,9(9):e99659. doi: 10.1371/journal.pone.0099659 URL
[4]	黄文忠, 王平平, 吴红照 , 等. BacT/ALERT 3D技术在结核杆菌耐药检测中的应用研究. 浙江预防医学, 2014,26(8):764-767.
[5]	徐东芳, 王庆 . BacT/ALERT 3D在结核分枝杆菌快速培养和药敏试验中的应用. 临床输血与检验, 2011,13(1):59-61.
[6]	Angeby KA, Werngren J, Toro JC , et al. Evaluation of the BacT/ALERT 3D system for recovery and drug susceptibility testing of Mycobacterium tuberculosis. Clin Microbiol Infect, 2003,9(11):1148-1152. doi: 10.1046/j.1469-0691.2003.00783.x URL
[7]	Abdel-Rahman SM, Erfan D, Abdel-Latif W , et al. Evaluation of Sensititre ^® MYCOTB panel for the susceptibility testing of Mycobacterium tuberculosis to first and second lines anti-tuberculosis drugs . Clinical Medicine and Diagnostics, 2016,6(1):13-19. doi: 10.4236/ojcd.2016.62003 URL
[8]	李静, 王智存, 白广红 , 等. MicroDST ^TM微孔板检测法对抗结核一、二线药物敏感性试验的临床价值 . 中华肺部疾病杂志(电子版), 2018,11(5):583-587.
[9]	王少华, 朱岩昆, 郑丹薇 , 等. 氧化还原指示剂法检测结核分枝杆菌耐多药和广泛耐药菌株的研究. 热带医学杂志, 2017,17(8):1012-1015.
[10]	周洪经, 郭明日, 冯爽 , 等. Xpert MTB/RIF在快速诊断肺结核及利福平耐药中的临床应用. 国际检验医学杂志, 2016,37(18):2568-2570.
[11]	赵冰, 欧喜超, 夏辉 , 等. Xpert Mtb/RIF检测技术在结核病诊断中的应用评价. 中国防痨杂志, 2014,36(6):462-466. doi: 10.3969/j.issn.1000-6621.2014.06.011
[12]	丁月荷, 卓玛, 李沛军 , 等. GeneXpert MTB/RIF技术对结核病和耐药结核病的诊断价值. 青海医药杂志, 2016,46(9):74-76.
[13]	魏淑贞, 林淑芳, 林建 , 等. GenoType MTBDRplus快速检测耐多药结核分枝杆菌复合群临床分离株效果评价. 中国人兽共患病学报, 2015,31(8):728-732. doi: 10.3969/cjz.j.issn.1002-2694.2015.08.009
[14]	王洪秀, 杨景卉, 王暖 , 等. GenoType MTBDRplus VER 2.0对痰样本结核分枝杆菌及其耐药性检测的应用评价. 检验医学, 2017,32(5):410-414.
[15]	孙倩, 张倩, 张治国 . Genotype MTBDRplus检测结核分枝杆菌耐药性的临床应用研究. 国际检验医学杂志, 2018,39(4):392-395.
[16]	Yadav RN, Singh BK, Sharma SK , et al. Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India. PLoS One, 2013,8(9):e72036. doi: 10.1371/journal.pone.0072036 URL
[17]	何建 . DNA微阵列芯片法检测耐药结核分枝杆菌的价值探讨. 传染病信息, 2018,31(1):38-40.
[18]	郝宝林, 邢进, 李辉 . DNA微阵列芯片法检测临床痰标本中结核分枝杆菌耐多药突变基因的研究. 医药论坛杂志, 2014,35(7):45-46.
[19]	张俊仙, 吴雪琼, 阳幼荣 , 等. 应用基因芯片方法检测结核分枝杆菌利福平和异烟肼的耐药性. 中国防痨杂志, 2011,33(10):680-685.
[20]	徐费凡, 顾德林, 瞿梅 , 等. 荧光PCR溶解曲线法快速检测结核分枝杆菌对利福平和异烟肼的耐药突变. 热带医学杂志, 2016,16(6):722-724.
[21]	马艳艳, 李辉, 赵东阳 , 等. 荧光PCR探针熔解曲线法检测结核分枝杆菌耐利福平突变研究. 中国国境卫生检疫杂志, 2011,34(6):451-454.
[22]	刘艳, 古丽比克·木拉提, 玛力亚木·阿布力提甫 , 等. 荧光PCR熔解曲线法检测结核分枝杆菌耐药基因的结果分析. 中国防痨杂志, 2018,40(9):959-963.
[23]	胡春梅, 郭晶, 严虹 , 等. 荧光定量PCR探针熔解曲线法在结核分枝杆菌耐药基因检测中的应用. 中国防痨杂志, 2016,38(1):38-41. doi: 10.3969/j.issn.1000-6621.2016.01.009
[24]	马晓光, 李辉, 石洁 , 等. 荧光PCR探针熔解曲线法检测结核分枝杆菌耐异烟肼突变. 现代预防医学, 2013,40(22):4201-4204,4207.
[25]	严虹, 施旭东, 胡春梅 , 等. 探针熔解曲线法快速检测结核分枝杆菌利福平、异烟肼、乙胺丁醇及链霉素耐药突变. 临床检验杂志, 2015,33(10):729-733.
[26]	王峰, 胡思玉, 桂静 , 等. PCR熔解曲线法筛查结核分枝杆菌链霉素和乙胺丁醇耐药性. 中华流行病学杂志, 2012,33(5):525-528.
[27]	李辉, 马晓光, 石洁 , 等. 荧光定量PCR探针熔解曲线法检测耐乙胺丁醇链霉素结核杆菌突变基因研究 //赵雁林.科学研究与结核病防治高峰论坛论文汇编, 延安, 2014: 92-97.
[28]	李国利, 李庆阁, 王倩 , 等. PCR-探针熔解分析法检测结核分枝杆菌氟喹诺酮耐药基因突变的临床应用评价. 中华临床医师杂志(电子版), 2011,5(16):4641-4645.
[29]	倪丽丽, 景玲杰, 杨景卉 , 等. 结核分枝杆菌对氟喹诺酮类药物敏感性的实验研究. 现代检验医学杂志, 2014,29(2):84-86.
[30]	彭亦平, 宗佩兰, 辛茶香 , 等. 应用PCR-反向点杂交技术快速检测结核分枝杆菌耐药突变基因. 中国防痨杂志, 2016,38(8):619-622.
[31]	邱可清, 沈学群, 高丽华 , 等. 基因芯片检测结核分枝杆菌耐药突变基因的结果分析. 吉林医学, 2014,35(17):3735-3737.
[32]	穆成, 王志锐, 赵慧 , 等. GenoType ^® MTBDRsl试剂盒检测Mtb对氧氟沙星耐药性的效果评价 . 中国防痨杂志, 2015,37(10):1081-1082.
[33]	Barnard M, Warren R, Gey Van Pittius N , et al. Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory. Am J Respir Crit Care Med, 2012,186(12):1298-1305. doi: 10.1164/rccm.201205-0960OC URL
[34]	Castan P, de Pablo A, Fernández-Romero N , et al. Point-of-care system for detection of Mycobacterium tuberculosis and rifampin resistance in sputum samples. J Clin Microbiol, 2014,52(2):502-507. doi: 10.1128/JCM.02209-13 URL
[35]	Cho E, Shamputa IC, Kwak HK , et al. Utility of the REBA MTB-Rifa assay for rapid detection of rifampicin resistant Mycobacterium tuberculosis. BMC Infect Dis, 2013,13:478. doi: 10.1186/1471-2334-13-478 URL
[36]	Santos PFGD, Costa ERD, Ramalho DM , et al. Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype ^® MTBDRplus . Mem Inst Oswaldo Cruz, 2017,112(6):396-403. doi: 10.1590/0074-02760160376 URL
[37]	Peng J, Yu X, Cui Z , et al. Multi-Fluorescence ^® Real-Time PCR assay for detection of RIF and INH resistance of M.tuberculosis . Front Microbiol, 2016,7:618.
[38]	Adikaram CP, Perera J, Wijesundera SS . DNA probe based colorimetric method for detection of rifampicin resistance of Mycobacterium tuberculosis. J Microbiol Methods, 2014,96:92-98. doi: 10.1016/j.mimet.2013.11.006 URL
[39]	Pholwat S, Stroup S, Foongladda S , et al. Digital PCR to detect and quantify heteroresistance in drug resistant Mycobacterium tuberculosis. PLoS One, 2013,8(2):e57238. doi: 10.1371/journal.pone.0057238 URL
[40]	郑瑞娟, 王洁, 秦莲花 , 等. 焦磷酸测序技术在利福平rpoB基因突变检测中的应用评价. 中华预防医学杂志, 2008,42(2):77-80.
[41]	Papaventsis D, Casali N, Kontsevaya I , et al. Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review. Clin Microbiol Infect, 2017,23(2):61-68. doi: 10.1016/j.cmi.2016.09.008 URL