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Chinese Journal of Antituberculosis ›› 2021, Vol. 43 ›› Issue (11): 1210-1215.doi: 10.3969/j.issn.1000-6621.2021.11.017

• Review Articles • Previous Articles     Next Articles

Research progress of correlation between pulmonary tuberculosis and intestinal flora

LI Kang, CHAI Ying-hui, BAI Guang-liang, DENG Xian-ping, LEI Hong()   

  1. Department of Clinical Laboratory, the Eighth Medical Center of PLA General Hospital, Beijing 100091, China
  • Received:2021-07-02 Online:2021-11-10 Published:2021-11-02
  • Contact: LEI Hong E-mail:leihong_hospitol@126.com

Abstract:

With the development of microbial detection technology, studies have found that there is a close relationship between intestinal flora and human diseases. At present, many studies have shown that the imbalance of intestinal flora exists in patients with pulmonary tuberculosis which may significantly increase the prevalence of pulmonary tuberculosis. They interact directly or indirectly through the metabolism of bacteria and the immune response of the body. The author reviews the relationship between pulmonary tuberculosis and intestinal flora, the possible mechanism of the interaction between them, and whether it is possible to prevent and treat pulmonary tuberculosis by regulating intestinal microflora.

Key words: Tuberculosis,pulmonary, Enterobacteriaceae, Metabolism, Immunomodulation, Beneficial bacteria