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Chinese Journal of Antituberculosis ›› 2020, Vol. 42 ›› Issue (11): 1250-1253.doi: 10.3969/j.issn.1000-6621.2020.11.019

• Review Articles • Previous Articles     Next Articles

Research progress of extracellular RNA of Mycobacterium tuberculosis

LI Ting, FAN Yun-fan, FU Ying-mei()   

  1. Department of Microbiology, Harbin Medical University, Harbin 150081, China
  • Received:2020-06-23 Online:2020-11-10 Published:2020-11-13
  • Contact: FU Ying-mei E-mail:fuyingmei@hrbmu.edu.cn

Abstract:

Tuberculosis has become one of the ten leading causes of death in the world. For tuberculosis,we urgently need an earlier diagnosis and a more effective treatment. Extracellular RNA (exRNA) has great potential as a biomarker and treatment for many diseases. In order to follow up on the application of Mycobacterium tuberculosis exRNA in the diagnosis and treatment of tuberculosis,we summarize the current research progress of Mycobacterium tuberculosis exRNA and discusse the production mechanism of Mycobacterium tuberculosis exRNA,hopefully to provide a favorable understanding for the exploration of Mycobacterium tuberculosis exRNA.

Key words: Mycobacterium tuberculosis, Extracellular RNA, Diagnosis, Therapeutic uses