Expert consensus on detection and clinical application of peripheral blood lymphocyte subsets in patients with tuberculosis

doi:10.3969/j.issn.1000-6621.2020.10.001

Abstract

Abstract:

The occurrence, development and prognosis of tuberculosis (TB) depend on the quantity and virulence of MTB and immune resistance. The analysis of lymphocyte subsets in peripheral blood of TB patients by flow cytometry can help to evaluate the immune status, immune function and immune balance of TB patients, and provide experimental basis for clinical development of immune intervention measures, observation of curative effect and judgment of prognosis. This expert consensus briefly introduces lymphocyte subsets analysis items (including percentage and absolute count) commonly used in clinic; puts forward the suggestions for the detection of lymphocyte subsets in TB patients and the correct interpretation of the results; introduces the use of lymphocyte subsets analysis in the clinical diagnosis and treatment of TB patients, and prospects the development of lymphocyte subsets detection in the future.

Key words: Tuberculosis, Lymphocyte subsets, Flow cytometry, Immunity, Laboratory techniques and procedures

Editorial Board of Chinese Journal of Antituberculosis. Expert consensus on detection and clinical application of peripheral blood lymphocyte subsets in patients with tuberculosis[J]. Chinese Journal of Antituberculosis, 2020, 42(10): 1009-1016. doi: 10.3969/j.issn.1000-6621.2020.10.001

Figures/Tables 1

References 60

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