Abstract:

Objective To understand the trend and epidemiological characteristics of newly reported pulmonary tuberculosis (PTB) cases in Guangzhou from 2008 to 2018. Methods Totally, 144473 information of newly reported PTB cases were collected from “China Information System for Disease Control and Prevention” from 2008 to 2018 in Guangzhou, including gender, age, occupation, regional distribution and pathogen classification. The annual and district resident population data of Guangzhou from 2008 to 2018 was derived from Guangzhou statistical yearbook. Descriptive analysis was conducted on the epidemiological characteristics of newly reported PTB in Guangzhou from 2008 to 2018. Results A total of 144473 PTB cases were newly reported from 2008 to 2018 in Guangzhou with an average annual newly reported incidence rate of 100.14/100000. The newly reported incidence declined from 148.44/100000 (16556/11153400) in 2008 to 67.58/100000 (10072/14904400) in 2018, which showed significant statistical difference ( {\chi }_{\mathrm{trend}}^2 =6849.75, P<0.05). Among the newly reported PTB cases in Guangzhou from 2008 to 2018, the male average annual newly reported incidence was 135.65/100000 (100003/73722700) with an annual decline rate of 7.56%, whereas the female average annual newly reported incidence was 63.04/100000 (44470/70547300) with an annual decline rate of 7.38%, which showed significant statistical difference (χ ²=18999.59, P<0.05). The 25- years old group reported the most cases in each age group, accounting for 23.88% (34505/144473). House worker and unemployed population were the most common occupations of all the newly reported cases, accounting for 23.82% (34416/144473) of the total cases. The newly reported incidence of smear positive PTB declined year by year, from 41.31/100000 (4608/11153400) in 2008 to 23.14/100000 (3449/14904400) in 2018. Conclusion Newly reported PTB cases in Guangzhou shows a decreasing trend year by year. It is necessary to strengthen the prevention and control of tuberculosis among male, young adults, house worker and unemployed population.

Key words: Tuberculosis,pulmonary, Incidence, Epidemiologic studies, Small-area analysis