Research progress of exosomal non-coding RNA as potential biomarkers of tuberculosis

doi:10.3969/j.issn.1000-6621.2020.03.019

Abstract

Abstract:

Tuberculosis is still a chronic infectious disease which is seriously harmful to human health. Exosome plays an important role in the occurrence and development of tuberculosis. Recently, more and more attention has been paid to the role of non-coding RNA in tuberculosis diagnosis. In this paper, the latest developments of exosome and Mycobacterium tuberculosis infection, exosomal non-coding RNA and tuberculosis diagnosis are reviewed, in order to provide a new idea for the study of early diagnosis, efficacy monitoring and prognosis estimation of tuberculosis from the perspective of exosomal non-coding RNA.

Key words: Tuberculosis, Exosomes, RNA probes, Biological markers, Review

GAO Shu-hui,ZHAO Jun-wei. Research progress of exosomal non-coding RNA as potential biomarkers of tuberculosis[J]. Chinese Journal of Antituberculosis, 2020, 42(3): 282-285. doi: 10.3969/j.issn.1000-6621.2020.03.019

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