Investigation and analysis of a school pulmonary tuberculosis aggregated epidemic in Chongqing

doi:10.19982/j.issn.1000-6621.20220099

Abstract

Abstract:

Objective: To investigate and analyze a school aggregated pulmonary tuberculosis epidemic in Chongqing and to provide thoughts and suggestions for the prevention and control of tuberculosis in schools. Methods: Descriptive epidemiological methods were used to investigate and analyze a school pulmonary tuberculosis epidemic in Chongqing from December 2020 to May 2021. Pulmonary tuberculosis screening was conducted with symptom screening, tuberculin skin test (TST) and chest X-ray, and epidemiological investigation of close contacts was also carried out. Results: After confirming 1 case of pulmonary tuberculosis with positive etiology (the index case), 8 active pulmonary tuberculosis patients and 42 latent tuberculosis infection patients were detected after 4 close contacts screening and 1 follow-up screening. All the 8 pulmonary tuberculosis students were concentrated in the class of the indicator case, with the incidence rate of 12.7% (8/63) and the etiological positive rate of 2/8. There were 34 latent tuberculosis infection patients, the latent infection rate of pulmonary tuberculosis was 61.8% (34/55), and all of them had completed preventive treatment. The incidence risk and infection risk of students in the class of the indicator case (RR=27.6, 95%CI: 13.5-56.4) were higher than those in other classes. Among the 8 cases of pulmonary tuberculosis in school, 6 were male, and 2 were female. The age distribution of cases was most in the 15-year old group (6 cases). Due to the poor quality of the chest X-ray of the first contact screening, the student patients were not found in time, resulting in the subsequent diagnosis of 3 patients. Two latent infected students were transformed into pulmonary tuberculosis patients during preventive treatment due to non-standard medication. Conclusion: The clustering of the epidemic was obvious. The low quality of screening and the failure to complete preventive treatment were important reasons for the spread of the epidemic. Therefore, when dealing with the school pulmonary tuberculosis epidemic, the quality of screening should be improved, the window period should be fully considered according to the epidemiological survey, and the standardization and completion rate of preventive treatment should be ensured.

Key words: Students, Tuberculosis, pulmonary, Epidemics

CLC Number:

R521
R81

Fan Jun, Su Qian, Chen Jian, Yu Ya, Wang Qingya, Zhang Ting, Cheng Jun, Feng Xinyu. Investigation and analysis of a school pulmonary tuberculosis aggregated epidemic in Chongqing[J]. Chinese Journal of Antituberculosis, 2022, 44(8): 792-796. doi: 10.19982/j.issn.1000-6621.20220099

Figures/Tables 2

References 20

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