Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions

Abstract

Abstract: Objective To explore the clinical significance of detecting P-selectin of pleural effusions in differentiating tuberculous and malignant diseases.Methods To detect the content of P-selectin in centrifuged supernatant of 48 cases with tuberculous pleural effusions and 50 cases with malignant pleural effusions by ELISA method.Results P-selectin of malignant pleural effusions (18.76±8.45μg/L) was distinctly higher than that of tuberculous pleural effusions (7.43±5.32μg/L) (P<0.01).Conclusion Detecting P-selectin of pleural effusion might be helpful for differentiating tuberculous and malignant diseases.

Key words: P-selectin, Pleural effusion, Enzyme-linked immunosorbent assay

ZHAO Yun feng,WANG Ying nian,GAO Dai qing,et al.. Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions[J]. Chinese Journal of Antituberculosis, 2002, 24(4): 200-202.

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Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions

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