Abstract: Objective  This study aims to summarize the evidence on the prevalence of tuberculosis (TB) disease among health care workers (HCWs), and to evaluate its associated factors. Methods  According to purposive sampling method，select 22 health institutions in Beijing, Inner Mongolia and Shanghai. Analyze data collected from HCWs who were investigated by questionnaires about TB infection control status between October and December in 2010. Results  A total of 5235 HCWs were investigated, the annual TB prevalence is 664.76/100 000(174/26 175) and the annual prevalence of smear-positive TB is 191.02/100 000(50/26 175).The result of logistic regression analysis indicates that male(Adjusted OR=1.9, 95%CI=1.3-2.7,P<0.05)、working in TB institutions (Adjusted OR=1.8, 95%CI=1.1-2.8,P<0.05)or lung hospitals(Adjusted OR=2.5, 95%CI=1.1-3.6,P<0.05)、working in TB out-patient(Adjusted OR=2.3, 95%CI=1.3-4.1,P<0.05)、the time of close contact with TB patients up to 15 hours per week (Adjusted OR=2.2, 95%CI=1.1-4.3,P<0.05)、without the system of TB infection control (Adjusted OR=1.7, 95%CI=1.2-2.3,P<0.05)、smoke(Adjusted OR=2.8, 95%CI=1.2-2.9,P<0.05) can increase the risk of Mycobacterium tuberculosis infection. Conclusion  The prevalence of TB in HCWs investigated was high, which indicates that the TB infection control measures are not enough. There is a need to strengthen the TB infection control practice to lower the Mycobacterium tuberculosis infection.

Key words: Tuberculosis, pulmonary/epidemiology, Disease transmission, patient-to-professional, Prevalence, Infection control