Abstract: ObjectiveTo study the clinical features and the correlated factors of secondary pulmonary tuberculosis complicated by fungi infection. MethodsThe clinical features and types of fungi strain in 508 patients with secondary pulmonary tuberculosis complicated by fungi infection were analyzed retrospectively. Results1.The major type of fungi infected in the patients with secondary pulmonary tuberculosis were Candida albicans whether infected with single type or mixed type of fungi(62% and 72%,respectively). 2.Patients with old age and long history were the major cases with secondary pulmonary tuberculosis whether infected with single type or mixed type of fungi（49% single and 55% mixed infection in elderly patients, 56% single and 65% mixed infection in long history patients）. 3. Whether infected with single type or mixed type of fungi，the incidence of fungi infection increased with the increase of lung lesion areas, especially lesion areas were more than three lung fields(61% and 75%, respectively).The patients with pulmonary tuberculosis complicated with fibrosis were easily infected by fungi(69% and 75%,respectively). 4. Whether infected with single or mixed type of fungi in patients with secondary pulmonary tuberculosis, Rale and moderate anaemia were seen in up to 50% patients and moderate fever was in up to 10% patients. ConclusionsCandida albicans was the major type of infected fungi in patients with secondary pulmonary tuberculosis. Patients with old age, long history and severe illness are major suspected population. The clinical features of most patients are atypical. The incidence of mixed infection with fungi in patients with secondary pulmonary tuberculosis is higher than that of patients with community acquired pneumonia.

Key words: Tuberculosis,pulmonary/complications, Lung diseases,fungal