Email Alert | RSS

Chinese Journal of Antituberculosis ›› 2008, Vol. 30 ›› Issue (4): 279-282.

Previous Articles     Next Articles

Clinical analysis of 62 cases with myeloid form tubercular meningitis in adult

Han Lijun,Yan Shiming,Guo Ziyuan,et al.   

  1. Changchun Infectious Hospital,changchun 130123,China
  • Online:2008-04-10 Published:2011-11-03

Abstract: Objective To discuss the clinical feature and treatment method of myeloid form tubercular meningitis(TBM) in adult. Methods To retrospectively analyze the 62 cases myeloid form tubercular meningitis in adult from 1999 to 2004. Results The percentage of myeloid form tubercular meningitis to tubercular meningitis in corresponding period patients was 13.9%.Main clinical manifestation were paraplegia,urination disorder and dysporia,disturbance of sensation result of conduction tract besides fever and meninges irritation symptom.Cerebrospinal fluid(CSF) circulation circuit was obstructed at various degree and CSF routine and biochemistry was not fully corresponding with albuminocytologic dissociation phenomenon and ADA activity rises obviously,cytology presents mix cell changed,but the percentage of neutrophil was relatively low,the average rate was 17.7%.Urination disorder and dysporia resumed earlier than paraplegia and the cure rate was 61.3%,case-fatality rate was 3.2%,the sequela rate was 35.5%,the recuring rate was 1.6%. Conclusion The cure rate of myeloid form tubercular meningitis is low and the sequela rate is high.Early discovery and effective treatment can prevent partly myeloid form tubercular meningitis.Anti-tubercular therapeutic schedule with mainly H,R,S(E),Z combined through 18~24 months apply to myeloid form tubercular meningitis,and feasible dose dexamethasone and long-period releasing cerebrospinal fluid combined with intrathecal injection can raise the cure rate of myeloid form tubercular meningitis.

Key words: myeloid form, tuberculosis,meninges