Abstract: Objective To evaluate the clinical curative effect of bacteriological positive pulmonary tuberculosis. Methods 169 primary and 90 re-treated bacteriological positive pulmonary tuberculosis cases were divided into groups A,B,C and D randomy.Group A(85 cases) and group B(84 cases) were treated with 2HRZS(E)/4HR;Group C(45 Cases) and group D(45 cases) were treated with 3HRZA(E)/6HR.Vaccae was added in Group A and Group C.Then observe the foci absorption and the sputum negative conversion. Results At the end of 3 months of treatment,the sputum negative conversion rate of groups A,B,C and D was 80.0%,65.5%,71.1% and 62.2% respectively.At the end of treatment,the sputum negative conversion rate of groups A,B,C and D was 97.6%,84.5%,95.6%and 77.8%;the foci absorption rate to groups A、B、C、D Was separately 90.6%,75.0%,82.2%and 60.0% respectively;Cavity close up rate was 85.9%,64.3%,77.8% and 57.7% respectively. Conclusion Vaccae can improve the sputum negative conversion rate,accelerate the foci absorption and improve the vitality of immune cells.It is a good immunity injection to be recommended for expansion usage.

Key words: Tuberculosis,pulmonary/therapy, Vaccae