Abstract: Objective To explore the valuation of pleural biopsy under gasgraphy by intubation for thoracic disease.Methods 44 inpatients which were no confirmed diagnosis by biopsy in the position pointed by routine ultrasonic,were placed a reserved catheter through central vein in thoracic cavity.Gas was injected through the catheter after pleural fluid was pumped out from the cavity.Then biopsy were done in the area of thickening pleural,which was pointed by X ray.Results The pathological positive rate of biopsy was 0 in the pleural specimens of the positions pointed by routine ultrasonic of 44 cases.The positive rate of thickening pleural by gasgraphy under X ray was 90.9%,and the pathological rate of biopsy was 97.5%.There were 12 cases with adenocarinoma,5 cases with malignant mesothelioma,22 cases of pulmonary tuberculosis.112 times of biopsy at the same site and different direction was taken,and there was no complication occurred.Conclusion The pleural lesion was easy to be found by gasgraphy through reserved intubation.The Results of biopsy was credibility and the positive rate was high.The method was safe,economical and could be popularized.

Key words: Catheter, Gasgraphy, Pleural biopsy