Abstract: Objective To investigate the relationship of concentration of pleural effusion in tuberculous exudative pleurisy with pleural thickness and adhesion.Methods 117 cases of primary tuberculosis pleurisy were divided into 3 groups (A、B、C) from low to high according to the content of fibrinogen concentration of pleural effusion.Pleural thickness were measured and the incidence rates of pleural adhesion were assessed during the course of treatment and after treatment.Results Pleural thickness indicators in the course of treatment:there was difference between group A and group B ( t=2.57,P<0.05 );there was significant difference between group A and group C ( t=7.15,P<0.01 );there was difference between group B and group C( t=2.46,P<0.05 ).The incidence rate of pleural adhesion in the course of treatment:there was no difference between group A and group B (χ²=3.51, P>0.05 );there was significant differencebetween group A and group C(χ²=9.87, P<0.01 );there was difference between group B and group C (χ²=4.51,P<0.05 ).Pleural thickness indicators after treatment:there was no difference between group A and group B ( t=1.45,P>0.05 );there was significant difference between group A and group C ( t=3.46,P<0.01 );there was signifcant difference between group B and group C ( t=2.89,P<0.01 );The incidence rate of Pleural adhesion after treatment:there was no differnce between group A and group B (χ²=0.10,P>0.05);there was difference between group A and group C(χ²= 4.36,P<0.05 );there was significant difference between group B and group C (χ²=7.49,P<0.01 ).Conclusion Pleural thickness and the incidence rate of pleural adhesion were effected by the content of the fibrin in pleural effusion.

Key words: Fibrinogen concentration determination, Tuberculous,pleura