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Chinese Journal of Antituberculosis ›› 2019, Vol. 41 ›› Issue (1): 95-101.doi: 10.3969/j.issn.1000-6621.2019.01.019

• Review Articles • Previous Articles     Next Articles

Research progress on cerebrospinal fluid examinations in early diagnosis of tuberculous meningitis

Sai-sai WANG1,Yan MA2,Yang LIU1()   

  1. 1.Department of Epidemiology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing 101149, China
  • Received:2018-10-24 Online:2019-01-10 Published:2019-01-09

Abstract:

Tuberculous meningitis (TBM) is the most serious type of extra-pulmonary tuberculosis, which usually causes higher mortality and disability rate. So early and rapid diagnosis of TBM, as well as differential diagnosis with other diseases are crucial for TBM treatment and its prognosis. In this paper, we did a systemically review on the research progress of cerebrospinal fluid testing application in early diagnosis of TBM and in differential diagnosis with pyogenic meningitis, viral meningitis (VM) and cryptococcul neoformans meningitis (CNM) in recent years, aiming to provide some ideas or references for the early diagnosis and differential diagnosis of TBM.

Key words: Tuberculosis, meningeal, Cerebrospinal fluid, Early diagnosis, Diagnosis, differential, Laboratory techniques and methods, Review