Abstract: Objective  To analyze the effect of PPM-DOTS(public TB control institution-public hospital mix for DOTS, PPM-DOTS) in case finding of multidrug-resistant tuberculosis (MDR-TB) cases and to explore the suitable strategy for MDR-TB case finding. Methods  The routine records for screening suspected MDR-TB patients in 2011 to 2012 were collected. Screening rate, detection rate and diagnosis time were used to evaluate the effect of PPM-DOTS in MDR-TB case finding. There were 2365 suspected MDR-TB cases detected in four program cities: 774 in Kaifeng, 761 in Lianyungang, 700 in Yongchuan district, Chongqing and 581 in Hohhot; the number for smear positive MDR-TB patients who came from CDC with complete dignosis time was 1608. Kruskal-Wallis H  was used to compare the case detection situation in different sites, 0.05 was set as the significance level. Results  The overall screening rate in the four sites was 83.98%(2365/2816). The detection rate with rapid test was 6.22%(147/2365). Generally, the medians of diagnosis time, time for sputum transportation, rapid test and information feed-back were 7 d, 2 d, 5 d and 0 d, respectively in four sites. The medians of dignosis time in Kaifeng, Lianyungang, Yongchuan district and Hohhot were 6 d, 7 d, 9 d and 14 d（H=275.19, P<0.001）. The medians of time for sputum transportation were 1 d, 2 d, 2 d and 2 d（H=104.92, P<0.001）, the medians of time for rapid test were 5 d, 4 d, 5 d and 6 d（H=8.19，P=0.042）, and the medians of the time for information feed-back were 0 d, 0 d, 0 d and 5 d（H=580.32, P<0.001）.   Conclusion  The screening rate and detection rate were in good levels, and the MDR-TB patients can be found in time. It is feasible and effective to identify MDR-TB cases by rapid diagnostic method to screen smear positive TB patients in PPM-DOTS settings, and this detection model is worthy learning and expanding.

Key words: Tuberculosis, pulmonary/prevention &, control, Tuberculosis, multidrug-resistant/prevention &, control, Mass screening