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Chinese Journal of Antituberculosis ›› 2012, Vol. 34 ›› Issue (9): 596-600.

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Systematic review on the management model for multi-drug resistant tuberculosis

WANG Ni,WANG Li-xia,ZHU Kun,LIU Er-yong,ZHOU Lin,CHENG Shi-ming,WAN Li-ya   

  1. National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
  • Received:2012-08-02 Online:2012-09-10 Published:2012-12-17
  • Contact: WANG Li-xia

Abstract: Objective  Systematic review on different international management model for multi-drug resistant tuberculosis and explore the strategies tailored to China.  Methods  Related publications, conference information and other materials were searched in PubMed, ProQuest, CHKD and WANFANG DATA (2000—2010),1151 studies were retrieved, except view articles, letters, news, editorials, reviews, bibliography and conference summary, 14 full-text studies and 3 published documents were included and analyzed.  Results  The results showed that there are mainly 4 kinds of management model:inpatient-based model,mainly implemented in the United States, France and other developed countries, patients are asked for receiving inpatient treatment (3 studies), outpatient-based model,patients are required to take examination and receive drug regularly in outpatient (1 studies), inpatient-outpatient based model,patients need to receive inpatient treatment throughout the intensive phase or until sputum bacteriological conversion, and then continued outpatient treatment (4 studies), and community-based model, mainly adopted in low and middle income countries, upgrades from the outpatient-based model and with emphasis on the NTP coverage (6 studies).  Conclusion  The model selection should base on the TB epidemic, economy, the coverage of NTP and the health care system. The inpatient-community-based management model should be developed for the management of drug resistant TB in China.

Key words: Tuberculosis,multidrugresistant, Disease management, Models,theoretical