Abstract: Objective  To explore the tuberculosis epidemic status in Panyu district of Guangdong province in order to provide evidence for tuberculosis control strategies development.  Methods  By using household clue method, a survey was conducted in all resident population of Donghuan street and Shilou township in Panyu district, 86 212 persons were investigated. The tuberculosis epidemic status was analyzed.  Results   (1)There were 89 active pulmonary tuberculosis cases among 86 212 persons investigated, among whom 33 smear positive cases and 29 new smear positive cases. (2) The prevalence rate of active pulmonary tuberculosis and smear positive tuberculosis were 103.23/100 000 and 38.28/100 000 respectively, with no significant difference of that with the 5th tuberculosis epidemiological sampling survey of Guangdong province. (3) The prevalence of active pulmonary tuberculosis in male and female were 123.11/100 000 and 85.53/100 000 respectively, there was no statistical significance. The prevalence  was higher in young and middle-aged people, and the prevalence of smear positive was higher in urban area with 67.94/100 000 than rural area（χ²=4.585，P=0.032）, although there was no significant difference of the prevalence rate of active pulmonary tuberculosis （142.06/100 000 and 94.26/100 000）. Conclusion  Panyu district still have high tuberculosis burden. National tuberculosis control strategy should be implemented thoroughly. The young people are still the key population in tuberculosis control in future.

Key words: Tuberculosis,pulmonary/epidemiology, Epidemiology studies, Guangzhou city