Abstract: Objective To explore the feasibility of the Morisky Medication Adherence Scale 8-item version (MMAS 8-item version) being applied on pulmonary tuberculosis (PTB) patients, and to measure and compare the adherence of PTB patients treated with fixed-does combination (FDC) and blister pack drugs. Methods In a randomized controlled clinical trial, the experimental group (EG) treated with FDC and the control group (CG) treated with blister pack drugs. MMAS 8-item version was applied to patients in both groups by questionnaire survey. Results Cronbach’s coefficient was 0.64 in this study. There were 230 patients in EG, and 233 in CG.. The adherence in EG was significantly higher than CG (Z=-6.001, P=0.000). Conclusion The adherence of PTB patients treated with FDC was better than those paitents treated with blister pack drugs. The MMAS 8-item version has a good reliability and sensitivity, could be applied on the PTB patients.

Key words: tuberculosis,pulmonary/drug therapy, patient compliance, drug administration schedale