Study on the incidence of cross resistance between rifampicin and rifabutin in Mycobacterium tuberculosis clinical isolates

Abstract

Abstract: Objective To determine the incidence of cross resistance between rifampicin and rifabutin by testing the minimal inhibitory concentrations(MICs) of rifampicin and rifabutin against Mycobacterium tuberculosis(M.tuberculosis) clinical isolates.Methods The liquid dilution method was performed to detect MICs of rifampicin and rifabutin in 116 M.tuberculosis clinical isolates.Results Rifabutin was susceptible to all isolates which were susceptible to rifampicin.Cross resistance between rifampicin and rifabutin w...

Key words: Rifabutin, Rifampicin, Cross resistance, MIC

CLC Number:

HAN Xi-Qin, HUANG Hai-Rong, LI Yan-Jing, YU Xia, BI Zhi-Qiang, CHU Nai-Hui, MA Yu. Study on the incidence of cross resistance between rifampicin and rifabutin in Mycobacterium tuberculosis clinical isolates[J]. Chinese Journal of Antituberculosis, 2010, 32(11): 740-743.

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Study on the incidence of cross resistance between rifampicin and rifabutin in Mycobacterium tuberculosis clinical isolates

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