Abstract: Objective To study the clinical feature and the cause of death in pulmonary tubercu- losis with multiple organ dysfunction syndromes.Methods To review and analyze of 45 cases of pulmonary tuberculosis with multiple organ dysfunction syndrome in research institute in the last 7 years.Results Damage of lungs(100%)was the most common feature;followed by damage in liver(68.8%),kidney (40.0%),brain(35.5%),heart(31.1%)and gastrointestinal(22.2%). Thirty-four patients were died.The main inducement was infection.The death cases mostly were respiratory failure,infectious shock and ARDS.Conclusions The early prevention and diagnosis, and integrated therapy are helpful in reducing mortality of severe pulmonary tuberculosis with mul- tiple organ dysfunction syndromes.

Key words: Pulmonary tuberculosis, Multiple organ dysfunction syndrome(MODS)