Abstract: Objective To observe the clinical efficacy and the adverse reactions of Compound Glycyrrhizin(Stronger Neo-Minophagen C) in the treatment of new pulmonary tuberculosis complicated with chronic Hepatitis B. Methods Sixty cases of new pulmonary tuberculosis complicated with chronic Hepatitis B were randomly divided into the treatment group(30 cases) and control group(30 cases).The both groups were treated with effective antitubercuolsis drugs.The treatment group was treated with Stronger Neo-Minophagen C,while the control group took glutathione. Results After two months treatment,the total effective rate of liver function improvement was 76.7% in the treatment group,and 46.7%(P<0.05) in the control group.The rates of clinical symptom and physical sign disappearance as well as distinct amelioration were 40% and 56.7% in the treatment group,and 26.7% and 46.7% in the control group,respectively.There were notable differences between the treatment group and the control group in the above mentioned aspects.Adverse reactions were rarely found. Conclusion Stronger Neo-Minophagen C is effective and reliable in improving liver function of patients suffering from new pulmonary tuberculosis complicated with chronic Hepatitis B during anti-tuberculosis chemotherapy.

Key words: Pulmonary tuberculosis/drug therapy, Chronic Hepatitis B/drug therapy, Compound Glycyrrhizin