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Chinese Journal of Antituberculosis ›› 2007, Vol. 29 ›› Issue (4): 314-316.

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Clinical analysis of 54 HIV/AIDS cases co-infected with pulmonary tuberculosis

Lu Ruichao,Xu Cailing,Li Qi.   

  1. Guangxi Longtan Hospital,Liuzhou 545005,China
  • Online:2007-04-10 Published:2007-11-03

Abstract: Objective To analyse the causes of death of HIV/AIDS cases co-infected with pulmonary tuberculosis(PTB) and to improve the level of clinical diagnosis and treatment.Methods The causes of death of 54 HIV/AIDS cases co-infected with PTB in all of 308 patients were analyzed retrospectively.Results There were 62 cases with CD4≥200/mm3,and 2 cases died;70 cases with CD4 100~199/mm3,and 8 cases died;82 cases with CD4 among 55~99/mm3,and 17 cases died;94 cases with CD4<50/mm3,and 27 cases died.There were 268 cases treated with anti-tuberculosis drugs,while 35 cases died;40 cases treated without anti-tuberculosis drugs,while 19 cases died.The main causes of death were fungus infection(28 cases),bacterial infection(10 cases),tubercle bacillus infection(6 cases),pneumocystis carinii infection(5 cases),viral infection(2 cases) and other causes(3 cases).Respiratory tract infection was the main cause.Conclusion The treatment of anti-tuberculosis may decrease the morality of these patients. When the level of CD4 is lower,the fatality is higher compared with CD4>100/mm3(P<0.05),fungus infection is the main cause of death of HIV/AIDS cases co-infected with pulmonary tuberculosis(PTB).Thus,the main Methods are anti-tuberculosis treatment at early stage,HAARTM,promoting immunity,and controlling other pathogenic infection,specially the fungus infection.

Key words: Pulmonary tuberculosis, AIDS