Abstract: Objective To observe the supplementary treatment effect of Yifeizhike capsule in treating re-treatment pulmonary tuberculosis(TB) patients. Methods Two hundred and Seventy-eight retreatment TB patients hospitalized from January 2001 to June 2004 were randomly divided into therapy group(140 cases) and control group(138 cases). The therapy group received chemical therapy and Yifeizhike capsule for 6months,while control group received chemical therapy only.The two groups received the same chemotherapy. Results At the end of 6 months,the sputum conversion rate was 82.8%(116/140) in therapy group and 63.0%(87/138) in control group(P<0.01);focus absorption rate in the chext X-ray film was 88.6%(124/140) in therapy group and 71.0%(98/138) in control group(P<0.01);the cavity close rate 70.8%(68/96) in therapy group and 53.9%(49/91) in control group(P<0.05).There was no obvious side effect in the two groups. Conclusion The supplementary treatment effect of Yifeizhike capsule is effective in treating re-treatment TB patients as a supplementary treatment,meanwhile there is no obvious side effect.The drug can be considered to be used in clinical practice.

Key words: Pulmonary tuberculosis/drug therapy, Chinese medicine,traditional