Abstract: Objective To evaluate the effects of bronchoscpic cryotherapy on endobronchial tuberculosis(EBTB).MethodsTwenty-one EBTB patients, cryotherapy and cather intervention compined with chemotherapy were performed through bronchofibroscope. Efficacy was assessed and followed up after treatment. ResultsTwenty-one patients with EBTB were treated 52 times by bronchoscpic cryotherapy. In 18 patients with granulomatous and ulcerative EBTB, intraluminal lesions disappeared thoroughly and the chinical symptoms improved completely and atelectasis or obstructive pneumonia disappeared.Only 3 patients leaved some intraluminal cicatrices. The significant improvement rate was 83.3%(15/18 patients), clinical effective rate was 16.7%(3/18 patients).The overall effective rate was 100%(18/18 patients).But,there were not significantly efficacy in 3 patients with cicatricial EBTB by bronchoscpic cryotherapy. ConclusionsBronchoscpic cryotherapy for granulomatous and ulcerative EBTB, could disappeared thoroughly the intraluminal lesions,and rapidly relieve chinical symptoms.Bronchoscpic cryotherapy is an effective and safe method of treatment in patients with EBTB.

Key words: Bronchofibroscope, Endobronchial tuberculosis,chemoftherapy