Abstract: Objective To explore the clinical features, approaches of endobronchial tuberculosis at early stage and the effects of cathether intervention treatmemt. Method Clinical symptoms,chest X-ray/CT scans and fiberoptic bronchoscopic(FB) findings and effects of cathether intervention of 246 cases with endobronchial tuberculosis were analyzed.Results Main symptoms were as follows:183 had cough,92 had expectoration with sputum,59 had light fever afternoon,78 had night sweat,84 had asthenia,67 had breathlessness,23 had blood-stained sputum.Chest X-ray and CT demonstrated:96 cases showed the bronchus narrowing,31 cases showed obstructive pneumonia,55 cases showed atelectasis,38 cases showed pulmonary cavity.Sputum smear and culture positive rate was 43.5% and 35.3% respectively. The culture positive rate of bronchial washings was 56.5%. Pathological confirmed TB in bronchoscopic biopsy specimens was 58.4%. Bronchoscpic Results showed exduative lesions in 42.2% of the cases,granulomatous in 10.2%,ulcerative lesions in 18.7% and cicatricial lesions in 17.1%. The sputum conversion rate at the end of 2, 6 months was 90.6% and 100% respectively. Conclusion We should provide chest X-ray and CT examinations for the suspects who have clinical manifestation as described above.Bronchoscopic was done when the patients were suspected. If there is no positive pathological and bacteriological results, anti-tuberculosis treatment could be done for testing the response and further diagnosis. Catheter intervention is reliable and safe method in the treatment of endomembrane pulmonary tuberculosis.

Key words: Tuberculosis,endobronchial, Fiberoptic bronchoscopic