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Chinese Journal of Antituberculosis ›› 2005, Vol. 27 ›› Issue (1): 47-50.

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The clinic study of the immune functions in AIDS complicated with pulmonary tuberculosis

Liu Yan,Yu Weiye,Wang Xiaoyan,et al.   

  1. Shenzhen East Lake Hospital,Shenzhen 518020,China
  • Online:2005-01-10 Published:2005-11-03

Abstract: Objective To investigate the damage of immune functions in AIDS complicated with pulmonary tuberculosis and to analysis the relationship between AIDS and tuberculosis to treat and prognosis.Methods Retrospective analysis was performed in 11 cases AIDS complicated with pulmonary tuberculosis patients hospitalized from May 1997 to March 2004 cases were tested T-lymphocyte subpopulation, PPD test and HIV-RNA. These tests Results were compared with 27 AIDS cases and tuberculosis 31 cases in the same time hospitalized.Results The CD4 and CD8 cell level in peripheral blood was statistical significance difference (P<0.01) in the AIDS with tuberculosis, and AIDS than tuberculosis.The CD3 cell level was no statistical significance (P>0.05). 6 cases HIV-RNA viral content in AIDS with tuberculosis was>3.0×106 copy/ml,5 cases HIV-RNA viral content<3.0×106 copy/ml.It was statistical significance (P<0.01)that it was compared with AIDS 27 cases (3cases>3.0×106 copy/ml,24cases<3.0×106 copy/ml). ALL patients alive expect for two patients dead of blood distribution of pulmonary tuberculosis.Conclusion The immune functions of AIDS complicated with tuberculosis were severe destroyed.The mortality was high in ADIS complicated blood distribution of pulmonary tuberculosis and terminal AIDS complicated with pulmonary tuberculosis. The study found AIDS complicated diffusion by blood of pulmonary tuberculosis and terminal AIDS complicated with pulmonary tuberculosis viral content was high, infective was serious, harm was verse. Treatment effect of anti-tuberculous was poor.

Key words: AIDS, Pulmonary tuberculosis/complicotion, Immune Function