Abstract: Objective To study on multiple organ injury pres en tation and treatment principle of SARS patients.Methods To anal yze the clinical data of 182 SARS patients with multiple organ injury in 429 cas es retrospectively.Results 174(95.6%) of all 182 patients had e xposure to SARS,and the incubation period ranged from 2 to 19 days.The clinical features included fever (99.5%),cough (64.3%),body pain (41.8%),dyspnea (26.9%), diarrhea (26.9%),headache (19.8%).There were differential acute lung injury (ALI ) in 182 cases and differential hepatic lesion in 152 cases and heart injury in 52 cases.Conclusion The morbidity of differential organ injury in SARS patients are different.The highest morbidity was lung injury and it has differential presentation in every stage.Most of cases with hepatic injury with mid level increased transaminase an d it was related to drugs.The injury of heart was directily invasion by SARS-Co V in early stage and it was relating to secondary immune reaction in late stage. The morbidity of kidney injury was the lowest.

Key words: SARS, Multiple organ failure