Abstract: Objective To explore the clinical feature,bacter ia distribution and treatment technology of pulmonary tuberculosis complicating wi th severe pneumonia.Methods The data of thirty five cases of pu lmonary tuberculosis complicating with severe pneumonia diagnosed by bronchoscop e with protected specimens brush (PSB) were analysed retrospectively.Results Clinical feature was high fever,purulent sputum,breathl ess,respiratory failure and high blood cell count.Xanthomonas maltophilia,anaero be and pseudomonas aeruginosa were the main pathogenic bacteria for infection.Th irty one cases were cured,four died,the fatality was 11.4%.Conclusion The clinical manifestation of pulmonary tuberculosis complicating with severe pneumonia was typical,had severely toxic symptoms.Bron choscope with PSB can provide accurate pathogenic diagnosis and guide using anti biotics.The complexing agent of third generation penicillin or cephalosporin and β-lactamase inhibitors and metronidazole were recommended to be used for cont rol of infection.Holding reasonably the indication and tactics of mechanical ve ntilation can increase cure rate.

Key words: Pulmonary tuberculosis/complication, Pneumonia