Abstract: Objective To observe the regulatory effect of traditional Chinese medicine on immune function of patients with neck tuberculous lymphnoditis after receiving regular anti-tuberculous treatment to explore its therapeutic mechanism.Methods Sixty relapse patients with neck tuberculous lymphnoditis after regular treatment with anti-tuberculous drugs were randomly divided into two groups,30 patients in each group.The treatment group were treated with traditional Chinese medicione (snakes and scorpions) only.The control group were treated with routine anti-tuberculous drugs (2DRtZE/7DRtE).T lymphocyte subsets of peripheral blood were determined before treatment and 1～6 months after treatment to compare the therapeutical effect in the two groups.Results The parameters of T lymphocyte subsets were improved in 20 patients within treatment group.After 6 months treatment,the parameters of T lymphocyte subsets were improved only in 5 patients within control group.There is a significant difference between two groups (P＜0.01).In the treated group,the total effective rate were 90%(27/30),clinical cure rate 53.3%(16/30).As compared with those in the control group,36.7%(11/30),10%(3/30) respectively,the difference was significant (P＜0.01).Conclusion Snakes and scorpions shows the regulatory effect on cellular immune function in patiens with neck tuberculous lymphnoditis failed after regular anti-tuberculous treatment.It could be increased the healing rate.Detumescence of lymphnoditis,healing of ulceration and the improvement of lesion on B-ultrasound in the treated group were better than that of the control group (P＜0.01).

Key words: Tuberculous lymphnoditis, Traditional Chinese medicion, Immune Function