Abstract: Objective To explore the influence to hepatic function caused by liver virus infection of tuberculosis cases during chemical anti-tuberculosis treatment and relative countermeasure.Methods Retrospective analysis on the clinical data of 1?746 pulomary tuberculosis cases(PTB) There were evidences on liver function damaged of 160 cases .Results 68 cases(38.64%)out of 176 PTB suffered with HBVM positive Were obsenred fo be damaged on their liver function.While 70(4.7%)out of 1490 suffers with HBVM negative.And among 80 cases without HBVM test,there were 22 cases(27.5%)with liver function damaged evidences.There was a significant difference( P <0.01)of liver tunction damaged incidence between HBVM positive and negative PTB cases.Most of the liver function dannaged were observed from 15 to 90 days after receiving treatment.Conclusion The liver virus infection during short-term chemical treatment will influence hepatic function.Testing HBVM and hepatic function is necessary before providing anti-tuberculosis treatment for the PTB cases.It is important to select some drug with minor side effections on liver function for the PTB cases with HBVM positive result.In the meantime,proper liver protection treatment,and closely observation on change of hepatic function should be taken.

Key words: Pulmonary,tuberculosis/treatment, Hepatitis B