Abstract: Objective To observe the effect of Levofloxacin on treating MDR-TB. Methods Divide 92 cases into two groups in a randomized way , 50 of them was study group , the rest was control group. Therapy for 2 groups were 3HKZThV/18HZTh and 3HKZTh/18HZTh respectively, then observe the changes in sputum bacteria , focus and symptoms of two groups.Results The rate of sputum bacteria negtive , focus shrinking and symptoms improving of study group were 40.0%,58.0%; 54.0% ,72.0%; 66.0%, 76.0% respectively after three months and six months. That of control group were 19.0%,35.7%;33.3%,42.9%;38.1%,45.2% respectively .There is significant difference between two groups(P<0.05).Conclusion Significant Results were achieved when choosing Levofloxacin combined with other medicine for treating MDR-TB enforcedly.

Key words: Levofloxacin(V), Multidrug Resistant,Tuberculosis(MDR-TB)