Abstract: Objective To discuss the effect of BGA by using low tidal volume maintained mechanical ventilation in elder patients with respiratory failure complicated by pulmonary tuberculosis.Methods Compared with the BGA Results in different tidal volume as 10 mL/kg,8 mL/kg,6 mL/kg for one hour and 6 mL/kg for 12 hours with the invariable mode and other parameters.Results PaCO₂ and PaO₂/FiO₂ was improved obviously when tidal volume was 6 mL/kg than before the mechanical ventilation ( P＜0.05).Conclusion Using low tidal volume mechanical ventilation can correct the respiratory failure effectively in the elder patients complicated by pulmonary tuberculosis.

Key words: Pulmonary tuberculosis, Mechanical ventilation, Tidal volume, Respiratory failure