Abstract: Objective To evaluate the clinical feature of pulmonary tuberculosis by rifampin-depending strains,the produce cause and avoid countermove. Methods The pulmonary tuberculosis by rifampin-depending strains were analyzed retrospectively.Results It was 60.5% (26/43) and 20.9%(9/43) in the age of 22～39 and 40～59 years group respectively,the percent rates was 88.4% (38/43) in the cases of focus scope ≥3 field of lungs:88.4%(38/43), caseation and vacuolation:58.1%(25/43),and the multidrug resistance was 88.4(38/43).The chemotherapy of 5 patients,all of primary treatment and multidrug resistance,was entire failure,and the failure rates of chemotherapy was 52.6%(20/38) in the 38 cases with relapsing patients.The abusing rate of rifampin was 76.3% in this group researched.Conclusion (1)It is main clinical feature that the patients possesses severe condition,multidrug resistance and bad prognosis.(2)That is major reason possible to abuse the drugs of rifampins.(3)To establish the method for rapid detection of drug resistance is the key to prevent producing rifampin depending strains.

Key words: Mycobacterium,tuberculosis, rifampin-depending growth, tuberculosis/lungs