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Chinese Journal of Antituberculosis ›› 2001, Vol. 23 ›› Issue (2): 81-84.

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Investigation of infection and onset of tuberculosis in children and youth after termination of BCG vaccination

WANG Hua jin,ZHOU Chang shan,WEI He ping,et al.   

  1. Fangshan District Antituberculosis Institute,Beijing 102400
  • Online:2001-02-10 Published:2001-11-03

Abstract: Objective To observe the infection and incidence of tuberculosis in children and youth after termination of BCG revaccination.Methods In 1998,PPD testing was conducted on 12 years old students from Fangshan district (BCG revaccination termination group) and Tongzhou district (BCG revaccination not termination group) of Beijing respectively,PPD reactions were measured at 72 hours,chest X ray examinations were performed on those with average diameter≥6mm indurations,acid fast bacillus detection was done for ones found exhibiting lung shadows and so on.Then,calculate tuberculosis infectious rate and morbidity according to PPD reaction intensity and finding of active tuberculosis patients.Results Morbidities of active pulmonary tuberculosis for BCG revaccination termination group and BCG revaccination not termination group were respectively 14.8/105 and 18.6/105 (P>0.05).Tuberculosis infectious rates:when criterion as diameter ≥15mm 7.9% and 19.6% respectively (P<0.005),and when criterion as diameter ≥20mm 3.9% and 4.2% respectively (P>0.05).Therefore,the two indicators used as reflecting tuberculosis infection and onset after BCG revaccination termination were both not higher and even lower than the BCG revaccination group.Conclusion BCG revaccination termination don’t increase tuberculosis infection and initiation in children and adolescents.It can spare a large amount of manpower,material recourses,and financial capacity.

Key words: BCG vaccination, Tuberculosis/epidemiology