Research progress of Mycobacterium tuberculosis exosome

doi:10.3969/j.issn.1000-6621.2018.10.018

Abstract

Abstract:

Since exosomes have been discovered in 1983, research on exosomes has been deepening, and their functions have been discovered constantly, such as diagnosing the occurrence of diseases as molecular markers and affecting the body’s immune function. Exosomes also exist in bacteria, which can affect the host immunity. When bacteria infect the host, the exosomes produced by the host also play a very important role in the host immunity. The function of exosomes of Mycobacterium tuberculosis is reviewed. In addition, the function of bacteria exosomes, represented by mycobacterium, is described.

Key words: Mycobacterium tuberculosis, Mycobacterium, Exosomes, Biological markers, Biomedical research, Functions

Xin-yang WANG,Ying-me FU,Yan-lin ZHAO,Feng-min ZHANG. Research progress of Mycobacterium tuberculosis exosome[J]. Chinese Journal of Antituberculosis, 2018, 40(10): 1129-1133. doi: 10.3969/j.issn.1000-6621.2018.10.018

Figures/Tables 2

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编号	蛋白名称	理论 Mw/pI	观察Mw/pI	序列覆盖 (%)	相配多肽 (个)	得分	倍数变化
P60709	肌动蛋白,细胞质1	42.0/5.29	40.7/5.13	24	7	100	1.78
P60709	肌动蛋白,细胞质1	42.0/5.29	40.6/5.10	22	8	100	2.31
P62873	鸟嘌呤核苷酸结合蛋白G (I)/G(S)/G(T)亚基β-1	38.1/5.60	36.8/5.70	8	2	56	1.97
P23528	钴纤维蛋白-1	18.7/8.22	12.01/8.66	34	5	167	1.92
P62937	肽基脯氨酰顺反异构酶A	18.2/7.68	11.53/8.31	50	10	136	2.13