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Chinese Journal of Antituberculosis ›› 2024, Vol. 46 ›› Issue (4): 473-478.doi: 10.19982/j.issn.1000-6621.20230400

• Review Articles • Previous Articles     Next Articles

Research progresses of interferon-induced protein 10 in the diagnosis and monitor of respiratory infectious diseases

Song Ruixue, Yao Mingxu, Pan Liping()   

  1. Beijing Key Laboratory for Drug Resistant Tuberculosis Research/Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China
  • Received:2023-11-06 Online:2024-04-10 Published:2024-04-01
  • Contact: Pan Liping E-mail:panliping2006@163.com
  • Supported by:
    Beijing Natural Science Foundation(L234055);Tongzhou Science and Technology Project(KJ2022CX042);National Natural Science Foundation of China(82172279)

Abstract:

Interferon inducible protein 10 (IP-10) is a member of the Cys-X-Cys (CXC) chemokine family, and its receptor is CXCR3. IP-10 has multiple biological functions, such as CXCR3+ cells, including chemotactic T cells, monocytes and NK cells, play roles in the process of pro-inflammation or anti-inflammation. It was found that IP-10 is also associated with respiratory infectious diseases, it plays a certain role in the diagnosis of tuberculosis infection, as well as monitor the progress of acute and serious respiratory infectious diseases such as novel coronavirus infection and highly pathogenic avian influenza. Therefore, the progresses of IP-10 in the diagnosis and monitor of respiratory infectious diseases were reviewed in this article.

Key words: Interferon inducers, Chemotactic factors, Noxae, Diagnosis

CLC Number: