Abstract:

Objective: To analyze the influencing factors of recurrence after successful treatment in new pulmonary tuberculosis (PTB) patients in Kashgar Prefecture, and to provide scientific basis for formulating intervention measures to reduce the recurrence of PTB in Kashgar Prefecture. Methods: Using the stratified cluster sampling method, as of December 31, 2021, 216 recurrent and 216 non-recurrent new PTB patients registered and successfully treated in Kashgar Prefecture in 2015 were selected as the survey objects and were matched 1∶1 according to gender and age. A questionnaire survey was conducted on those 432 patients, and multivariate logistic regression was used to analyze the main influencing factors of PTB recurrence after successful treatment. Results: Multivariate logistic analysis indicated: body mass index>24.00 (OR=4.235, 95%CI: 1.277-7.877), education level being new school (OR=3.434, 95%CI: 1.861-6.337), middle-income (OR=2.240,95%CI: 1.256-3.993), unstandardized anti-TB treatment (OR=3.436, 95%CI: 1.788-6.606), smoking (OR=3.970, 95%CI: 1.419-11.113) were independent risk factors for TB recurrence. Patients with no history of close contact with other TB patients (OR=0.256, 95%CI: 0.137-0.477) and patients receiving centralized medication (OR=0.103, 95%CI: 0.026-0.413) were less likely to recurrent. Conclusion: Implementing centralized medication management for tuberculosis patients in Kashgar Prefecture, and timely implementation of targeted interventions for smokers and people with a history of close contact with other TB patients, can effectively reduce the recurrence of PTB.

Key words: Tuberculosis, pulmonary, Recurrence, Factor analysis, statistical