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Chinese Journal of Antituberculosis ›› 2022, Vol. 44 ›› Issue (12): 1358-1362.doi: 10.19982/j.issn.1000-6621.20220282

• Review Articles • Previous Articles     Next Articles

Research progress of non-coding RNA tuberculosis

Zhu Yinyin1,2, Zhang Hongying1,2()   

  1. 1Microbiological Laboratory, Nanjing Center for Disease Control and Prevention Affiliated to Nanjing Medical University, Nanjing 210003, China
    2School of Public Health Nangjing Medical University, Nanjing 211166, China
  • Received:2022-07-27 Online:2022-12-10 Published:2022-12-02
  • Contact: Zhang Hongying E-mail:xiao99now@aliyun.com
  • Supported by:
    Health Standards Assessment Project of China Center for Disease Control and Prevention Public Health(2021-05-20);Medical Key Science and Technology Development Project of Nanjing Municipal Health Commission(zkx2019048)

Abstract:

Tuberculosis, a chronic infectious disease caused by Mycobacterium tuberculosis, is one of the most serious infectious disease in the world. Despite significant advances in detection techniques and therapeutic approaches for tuberculosis, there is still lack of early screening methods and targeted treatment. Non-coding RNA (ncRNA) widely participate in various biological processes, including Mycobacterium tuberculosis infection, and play critical roles. In view of the interaction of the host with Mycobacterium tuberculosis, the author reviewed research progress and regulation mechanism of host ncRNA in the tuberculosis infection process in human and regulation mechanism, to bring potential clinical prospects for tuberculosis diagnosis and the development of new anti-tuberculosis therapies.

Key words: Mycobacterium tuberculosis, RNA probes, Biological markers, Review

CLC Number: