231例脊柱结核患者耐药情况分析
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王潮虹, 孙晴, 廖鑫磊, 晏君, 王晨倩, 姜广路, 王芬, 薛毅, 黄海荣, 王桂荣
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Analysis of drug resistance situation of Mycobacterium tuberculosis strains from 231 spinal tuberculosis patients
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Wang Chaohong, Sun Qing, Liao Xinlei, Yan Jun, Wang Chenqian, Jiang Guanglu, Wang Fen, Xue Yi, Huang Hairong, Wang Guirong
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表2 不同任一耐药类型在初治和复治脊柱结核患者中的分布
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| 耐药类型 | 合计(231例) | 初治患者(174例) | 复治患者(57例) | χ2值 | P值 | | 任一耐药 | 80(34.63) | 37(21.26) | 43(75.44) | 55.660 | <0.001 | | Sm | 57(24.68) | 24(13.79) | 33(57.89) | 44.930 | <0.001 | | INH | 52(22.51) | 13(7.47) | 39(68.42) | 91.440 | <0.001 | | RFP | 42(18.18) | 10(5.75) | 32(56.14) | 73.290 | <0.001 | | EMB | 9(3.90) | 0(0.00) | 9(15.79) | 28.590 | <0.001 | | Rft | 44(19.05) | 11(6.32) | 33(57.89) | 74.060 | <0.001 | | Lfx | 18(7.79) | 5(2.87) | 13(22.81) | 23.740 | <0.001 | | Am | 8(3.46) | 3(1.72) | 5(8.77) | 4.450 | 0.035 | | Cm | 13(5.63) | 7(4.02) | 6(10.53) | 2.300 | 0.129 | | Pto | 10(4.33) | 4(2.30) | 6(10.53) | 5.170 | 0.023 | | Pa | 36(15.58) | 8(4.60) | 28(49.12) | 64.701 | <0.001 | | Mfx | 6(2.60) | 1(0.57) | 5(8.77) | 8.393 | 0.004 | | PAS | 17(7.36) | 9(5.17) | 8(14.04) | 3.732 | 0.053 | | Clr | 10(4.33) | 5(2.87) | 5(8.77) | 2.232 | 0.127 | | Rfb | 32(13.85) | 6(3.45) | 26(45.61) | 63.967 | <0.001 | | Km | 11(4.76) | 4(2.30) | 7(12.28) | 7.360 | 0.007 | | Cfz | 11(4.76) | 4(2.30) | 7(12.28) | 7.360 | 0.007 |
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