系统性红斑狼疮合并结核感染临床特征及外周血淋巴细胞亚群分析

谢静仪, 邹瑞丰, 陈玉兰, 陈永, 刘冬舟, 洪小平

Analysis of clinical features and peripheral lymphocyte subsets of systemic lupus erythematosus patients complicated with tuberculosis infection

Xie Jingyi, Zou Ruifeng, Chen Yulan, Chen Yong, Liu Dongzhou, Hong Xiaoping

表3 外周血淋巴细胞亚群比例在系统性红斑狼疮组及对照组中的分布情况

淋巴细胞亚群比例 [%,M(Q1,Q3)] SLE合并活动性 结核病组(30例) SLE合并LTBI 组(16例) SLE未合并 感染组(60例) 对照组 (40名) Z值 P值 CD3+ T细胞 74.35(65.50,81.18) 84.70(76.10,89.45) 79.50(71.55,86.08) 73.75(69.22,78.85) 13.948 0.003 CD4+ T细胞 31.20(27.10,39.02) 39.20(35.80,45.95) 35.30(27.5,42.58) 42.2(37.78,46.82) 19.566 <0.001 CD8+ T细胞 30.45(24.45,43.12) 36.00(21.78,48.42) 35.15(29.72,43.42) 24.25(20.85,30.12) 34.383 <0.001 CD19+ B细胞 9.65(6.80,16.72) 6.25(4.58,9.65) 10.70(6.35,16.95) 13.50(9.78,15.92) 8.482 0.037 NK细胞 11.80(5.12,16.95) 5.65(2.80,11.20) 7.00(3.92,10.90) 11.85(7.48.16.70) 19.207 <0.001