Abstract: Objective To observe Bi-level positive airway pressure ventilation（BiPAP ventilation）the treatment effects in pulmonary tuberculosis patients with respiratory failure. Methods Thirty-one patients treated by BiPAP on the basis of routine treatment were enrolled in the treatment group.The efficacy was evaluated and compared with 20 similar patients is the control group. Results After BiPAP ventitalion the PaO2 and PaCO2 were greatly improved in treatment group（P<0.01）.PaO2 was also increased in control group.There was no significantly difference after routine therapy. Conclusion BiPAP ventitalion can improve the PaO2 and PaCO2 and relieve symptom especially to respiratory muscle fatigue.It is a supplementary measure to treat pulmonary tuberculosis patients with respiratory failure and it can prevent the incidence of pulmonary encephatopathy.

Key words: BiPAP, Pulmonary tuberculosis/complication, respiratory failure