Abstract: Objective To study the value of three kinds of tuberculous antibodies in diagnosis of pulmonary tuberculosis,tuberculous meningitis and tuberculous pleurisy. Methods Select ICT-TB card,TB-DOT produced by Austrilia and homemade ELISA to detect tuberculous antibodies of 220 patients with pulmlonary tuberculosis,56 tuberculous miningitis,36 tuberculous pleurisy had been observed comparatively with 48 cases of non-tuberculosis lung diesase(serum),17 cases of non-tuberculosis meningitis brain disease(CSF),18 patients with pleurisy except tuberculosis(pleurorrhea),30 healthy individuals(serum). Results The sensitivity was 50.7%,52.7%,58.7%,there was no significant difference (P>0.05) in Results detected by three kinds. The specificity was 97.3%,93.2%,79.7%,there was no singnificant difference (P>0.05). The sensitivity of ICT-TB card in serum of pulmonary tuberculosis,tuberculous meningitis and tuberculous pleurisy was 57.2%, 46.4%,30.6%,TB-DOT was 60.0%,44.6%,33.3%,ELISA was 68.2%,42.9%,38.9%. There was significant difference (P<0.005,P<0.05). To compare the sensitivity of three kinds to detect three kinds of body fluid with each other,the serum was highest (57.2%～68.2%), CSF was second(51.8%～55.4%),the pleurorrhea was third (31.6%～50.0%). Conclusion The specificity of ICT-TB card and TB-DOT is higher but the sensitivity is lower. On the contrary,the sensitivity of ELISA is higher and the specificity is lower. But in fact,the value in clinical is similar. To detect tuberculous antibodies in diagnosis of pulmonary tuberculosis is more valuable than in tuberculous meningitis and tuberculous pleurisy.

Key words: Tuberculosis,pulmonary/Diagnosis, Antibodies,Mycobacterium, Tuberculosis,Meningeal,Tuberculosis,pleural