Abstract: ObjectiveTo investigate clinical diagnosis and treatment for patients with pulmonary tuberculosis complicated with lower respiratory tract infection with hypermastigote. MethodThe clinical manifestations, imaging findings, laboratory Results and treatment were studied for 7 patients with pulmonary tuberculosis complicated with lower respiratory tract infection with hypermastigote. ResultsThe main symptoms were cough and fever. The fever and obvious night sweat were still existing after regular anti-tuberculosis treatment. Sediment smear examination of bronchoalveolar lavage fluid was helpful to increase the positive rate of hypermastigote. Metronidazole had good therapeutic effect with improving fever and night sweat. ConclusionThe patients with pulmonary tuberculosis complicated with lower respiratory tract infection with hypermastigote is not rare in Shenzhen area. Improving understanding, early diagnosis and timely treatment will bring better prognosis.

Key words: Tuberculosis,pulmonary/complications, Mastigophora infections