Abstract: Objective To review problems related to the liver damages of treatment regimens of the tuberculosis control project for ensuring the implementation of the project smoothly.Methods Retrospective analysis had been done for the 282 cases with liver damage symptoms out of the 1?654 smear-positive cases who received the anti-tuberculosis treatment from 1998 to 2002.Results The highest rate of liver damage casued by anti-tuberculosis drugs was occurred in 35-75 year (210 cases,74.5%).Digestive tract symptom and liver function changes that appeared within two months in 90% cases.For the cases with less serious changes,liver-protection treatment was used and no need to stop anti-tuberculosis treament.For the cases who with serious changes,liver-protection treatment was used and the anti-tuberculosis treatment courses (97.5%).Conclusion The side-effect of the anti-tuberculosis can be figured out and countermeasure of prevention and cure be mastered so that the Tuberculosis treatment courses would be successfully completed.Lives of the patients would be saved and medical care disputes can be avoided.

Key words: Pulmonary tuberculosis/prevention and control, Chemotherepy, Liver damage