Progress in clinical application of molecular pathological diagnosis of tuberculosis

doi:10.3969/j.issn.1000-6621.2018.11.014

Abstract

Abstract:

Pathology plays important roles in diagnosis of tuberculosis, especially in intractable cases such as sputum-negative pulmonary tuberculosis and extrapulmonary tuberculosis. “ Chinese Expert Consensus on Pathological Diagnosis of Tuberculosis” published in 2017 pointed out that definite pathological diagnosis of tuberculosis should meet both of the criteria: (1) basic tuberculous histological changes are found, (2) definite etiological evidences are confirmed by molecular pathology. In recent years, molecular pathological techniques play more and more important roles in the diagnosis and differential diagnosis of tuberculosis. The author reviews the progress of molecular pathological techniques in diagnosis of tuberculosis, non-tuberculous mycobacterial diseases, and drug-resistant tuberculosis.

Key words: Tuberculosis, Pathology, Molecular, Diagnostic techniques and procedures, Review litera-ture as topic

SONG Jing,CHE Nan-ying. Progress in clinical application of molecular pathological diagnosis of tuberculosis[J]. Chinese Journal of Antituberculosis, 2018, 40(11): 1221-1225. doi: 10.3969/j.issn.1000-6621.2018.11.014

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