Epidemiological characteristics of inactive pulmonary tuberculosis among the elderly in high-endemic rural areas in Quzhou City, Zhejiang Province

doi:10.19982/j.issn.1000-6621.20220128

Abstract

Abstract:

Objective: To analyze the epidemiological characteristics of inactive pulmonary tuberculosis among the elderly in high tuberculosis endemic rural areas in Quzhou, Zhejiang Province. Methods: The elderly population aged 65 and above who lived for at least 6 months in 6 administrative villages in 2 townships in Quzhou City, Zhejiang Province with high incidence of tuberculosis, were recruited. Free digital radiography (DR) screening and gamma-interferon release assays (IGRA) were performed to detect latent infection of Mycobacterium tuberculosis and screen inactive pulmonary tuberculosis, thus to obtain the prevalence of inactive pulmonary tuberculosis in the elderly people and analyze characteristics of patients and detection positive rate. Results: A total of 2050 subjects met the enroll criteria, and 1658 completed all screening tests, with a screening rate of 80.88% (1658/2050). The detection positive rate of inactive pulmonary tuberculosis was 8.62% (143/1658), the detection rate of active pulmonary tuberculosis was 0.24% (4/1658). The proportion of detected with inactive pulmonary tuberculosis in the elderly male (63.64%, 91/143) significantly higher than females (36.36%, 52/143), and the difference was statistically significant (χ²=12.161, P=0.000). The detection positive rate increased from 5.60% (34/607) among 65-69 years age group to 12.20% (10/82) among 85 years old and above age group, and the difference was statistically significant ( $χ t r e n d 2$ =12.329, P=0.000). The incidence rate of pulmonary fibrous lesions among inactive pulmonary tuberculosis patients (62.94%, 90/143) was significantly higher than that of the general population (13.04%, 197/1511,χ²=226.817, P=0.000). Conclusion: The detection positive rate of inactive pulmonary tuberculosis in rural elderly people in high tuberculosis incidence areas in Quzhou City, Zhejiang Province is rather high. Scientific researches should be continued to monitor the risk characteristics of the disease, so as to provide basic data for formulating local intervention measures to lower the epidemic.

Key words: Tuberculosis, pulmonary, Mycobacterial infection, Tomography, X-ray computed, Elderly

CLC Number:

R521
R81

Zhu Ping, Hao Xiaogang, Wang Wei, Chen Bin. Epidemiological characteristics of inactive pulmonary tuberculosis among the elderly in high-endemic rural areas in Quzhou City, Zhejiang Province[J]. Chinese Journal of Antituberculosis, 2022, 44(8): 815-820. doi: 10.19982/j.issn.1000-6621.20220128

Figures/Tables 4

References 20

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行政村	老年人总数 (名)	老年人筛查数(名)	活动性肺结核		非活动性肺结核		LTBI
行政村	老年人总数 (名)	老年人筛查数(名)	检出例数	检出率(%)	检出例数	检出率(%)	检出例数	检出率(%)
江山市
上王村	245	213	1	0.47	25	11.74	97	45.54
潭边村	541	470	1	0.21	48	10.21	165	35.11
占村	276	241	0	0.00	21	8.71	76	31.54
常山县
古田畈村	125	109	0	0.00	9	8.26	28	25.69
五里村	290	220	1	0.45	16	7.27	86	39.09
象湖村	573	405	1	0.25	24	5.93	126	31.11
合计	2050	1658	4	0.24	143	8.62	578	34.86

年龄组 (岁)	男性			女性			总计
年龄组 (岁)	筛查数(名)	检出例数	检出率(%)	筛查数(名)	检出例数	检出率(%)	筛查数(名)	检出例数	检出率(%)
65~69	288	22	7.64	319	12	3.76	607	34	5.60
70~74	270	33	12.22	263	19	7.22	533	52	9.76
75~79	143	16	11.19	132	7	5.30	275	23	8.36
80~84	91	13	14.29	70	11	15.71	161	24	14.91
≥85	32	7	21.88	50	3	6.00	82	10	12.20
合计	824	91	11.04	834	52	6.24	1658	143	8.62

年龄组 (岁)	男性			女性			总计
年龄组 (岁)	LTBI(例)	检出数(例)	检出率(%)	LTBI(例)	检出数(例)	检出率(%)	LTBI(例)	检出数(例)	检出率(%)
65~69	110	22	20.00	94	12	12.77	204	34	16.67
70~74	115	33	28.70	81	19	23.46	196	52	26.53
75~79	51	16	31.37	35	7	20.00	86	23	26.74
80~84	37	13	35.14	25	11	44.00	62	24	38.71
≥85	15	7	46.67	15	3	20.00	30	10	33.33
合计	328	91	27.74	250	52	20.80	578	143	24.74

患者特征	总例数	纤维性病灶(例)	硬结性病灶(例)	钙化病灶(例)	胸膜病灶(例)
性别
男性	91	52	24	12	3
女性	52	38	6	4	4
年龄组(岁)
65~69	34	21	4	7	2
70~74	52	32	13	5	2
75~79	23	16	4	2	1
80~84	24	16	7	0	1
≥85	10	5	2	2	1